His life cancer has rare side effects

For a long time, difficult problems with therapy related to cancer.He also emphasized the action that can be changed for genetic changes in the development of the tumor.

The international research team, including Prof.Insten Küberr of the Institute of Berlin Health in Charit (BIH) and collaboration of funds, and Harvard, General Tamoxifen who is not known can produce a risk of tumors in the womb.

According to the study, Tamoxyphen directly stimulates the main cell-based passage (Pi3k), which indicates the main driving crucial driviation of the early driviation of the early driviation of the early driviler.

Life saving medicine with a few complications

Since the 1970s, Tamoxifen has played a central role in improving the survival of millions with positive breast cancer.Despite its effectiveness, the drug was rarely associated with the specific molecular cause.

The research provides clear: in uterine cancer associated with pamoxifin, the mutations in the genetic genes associated with cancer-which are usually common in uterine tumors that spontaneously and activate the activation of Pi3K tombs are much lower.These mutations drive the development of the tumor.

"Our answer is for the first time that the activation of a drug tumor is possible and provides molecular drugs can promote the development of other tissues," explains Prof.kirsten Kübler, leader of the research group in Bih."Tamoxifen has followed the business in PI3K to mark Palfway, by directing the tumor."

Improve therapeutic security

While growing a lower risk of treatment during treatment - and demonstrations are based on the treatment of treatment.

In future projects, researchers are planning to check if the same processes can play a similar role in other drug side effects.

Reference Kubar, egostina Naauron, Janjig, Marjagli, All S.Fagli, Elder S.Fail, All S.Fagli, Elderly 2025, the genetic nature.

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