A protein consisting of worse was Alzheimer's illness and exciting

For decades, Alzheima's story found a position between A-beitads, both can kill neurons and affect the brain energy.

More incorrectly folded proteins contribute to Alzheimer's and dementia than previously known

Over the decades, the story is dominated in Alkhymer in the fight between A-Beru, but all models can kill you.

Researchers at the University of John Hopkins have identified more than 200 different types of proteins in rats that may be related to age -related knowledge and understanding.

The results can pave the way for new objectives and therapeutic treatment for humans who can provide relief for millions of people over the age of 65 who suffer from Alzheimer's, dementia or other diseases that rob them of their memories and independence when they are older.

"Amyloids are the accumulation of the wrong protein. They are large and ugly and easily visible under the microscope, so it makes sense that they attract our attention. But we see hundreds of proteins mistakes that combine amyloid and still affect cerebral functions," said Stephen Fried.

"Our studies show that Amson is the tip of Iceberg."

The results are published in the science progress.

To understand the molecular differences between the old brains, which are mentally sharp, and those who suffer from a drop, Fried and his team have studied 17 two -year rat in the same colony.See-Seven rats performed poorly memory and problem-solving tests and were considered cognitively weakened, while 10 were performed, as well as six months of rats.

Then the researchers measured 2500 types of proteins in the hippocampus, which is associated with spatial practice and memory.

For the first time, the scientists can describe the number of proteins or individual proteins and meet with all raters and especially in cognect.

If the forms and high and high, more proteins are defined in size without a string.Researchers show that some researchers help the subtes, and researchers say.

Wrong protein is not able to perform the necessary functions required to properly operate a cell, so that cells have a natural monitoring system that identifies and destroys these poor proteins.Almost, researchers thought of wrong protein.

"I hope that you do not create ammailoids and not causing problems may be illegal."She said."To"

But exactly how it slipped in front of the security system of the wrong protein cell remains a mystery.

Next, the group plans to examine the most installed proteins under the higher microscopes to find a more detailed image for what they look like Molhales levels.

"Many of us have suffered from a family member or a relationship that has become so much to do these daily activities that need the skills," CARD says.

“Understanding what’s going on in the brain leads to better care and preventive measures.”

Further information: Haley Tarbox et al., Structural changes in the rat -aging model show reduced overload, Science Progresses (2025).