The term rare defines a disease that affects a small number of people and unfortunately there are thousands of them. The number of known and diagnosed rare diseases ranges from 7000 to 8000, but they are also increasing due to new research. According to the data, in Italy it is estimated at 20 cases per 10,000 inhabitants, and every year there are many new cases reported by health facilities.
Many of them are of genetic origin, others are autoimmune or due to infection. Scientific knowledge is still scarce, and there are no effective treatments for the vast majority, but only treatments that improve quality of life. The Istituto Superiore della Sanità has specified a list of rare diseases to be exempted from the ticket. Exactly as described in the article 2021 Ticket Exemption Without ISEE for These INPs Recognized Diseases.
It can happen, when certain initial symptoms are encountered, that a diagnosis of cheating is reached or when the symptoms become severe. Example? A burning, intimate pain can signal the onset of this bothersome and disabling physical condition. Initial symptoms, such as an urge to urinate and pain when urinating, may suggest at first classic cystitis. However, a thorough investigation may reveal one interstitial cystitis (painful bladder syndrome) which, unlike cystitis, occurs in the absence of a bacterial load. Since 2001, this syndrome has been recognized as a rare disease by ministerial decree.
A burning and intimate pain can signal the beginning of this bothersome and disabling physical condition
This disease is a chronic condition that occurs without a bacterial infection. It causes severe pain localized in various places such as the urethra, bladder, perineum and sometimes spreading to the abdomen and legs. The pain can be intermittent or continuous, to the point that it is also detrimental to social and emotional life. This condition can affect both men and women of any age, although it is more common in the latter age group. It has a slow development but gradually gets worse.
The causes of this condition remain unclear, and it is assumed that surgery or viral illness may contribute. The most supported hypothesis is that of the thinning of the walls of the bladder that act as protection. Due to this dilution, the irritants present in the urine attack the walls causing inflammation.
It is very important to get acquainted with it in time, in order to avoid even serious consequences. However, diagnosis can take some time, as symptoms are often associated with other disorders. Thanks to continuous research, innovative and targeted treatments have been developed that can help better deal with this condition. Treatments may include taking medications by mouth, or intravesical with instillation of solutions based on hyaluronic acid and chondroitin sulfate.
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